Chiron approach for the synthesis of (1 S,2 R,5 R,7 S)-2-hydroxy- exo-brevicomin

D Gautam,D Naveen Kumar,B Venkateswara Rao

doi:10.1016/j.tetasy.2006.02.020

Chiron approach for the synthesis of (1 S,2 R,5 R,7 S)-2-hydroxy- exo-brevicomin

D Gautam, D Naveen Kumar + Show 1 more

https://doi.org/10.1016/j.tetasy.2006.02.020

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Journal: Tetrahedron: Asymmetry	Publication Date: Mar 1, 2006
Citations: 15

Affiliation: Indian Institute of Chemical Technology

#Key Reaction #Formation Of Ketal + Show 4 more

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Abstract

(1 S,2 R,5 R,7 S)-2-Hydroxy- exo-brevicomin ent- 1 was synthesized from 1,2;5,6-di- O-isopropylidene- d-glucose in seven steps. The key reaction in our synthesis is the formation of bicyclic ketal 7 under acid mediated acetal exchange of a 1,2-acetonide of d-glucose derivative 6.

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