Chiral Recognition of l-Gramicidine on Chiraly Methionine-Modified Au(111).

Abstract

A chiral pentadecapeptide, l-gramicidine, has been shown to undergo specific adsorption onto gold surfaces modified by chiral amino acids, d- and l-methionine, upon adsorption in the liquid phase. There is a chiral recognition only between the slightly anionic l-peptide and the l-modified surface exhibiting cationic molecules. However, whatever the probe and target molecule charges, very weak recognition was observed between molecules of opposite chirality.