Chiral electroorganic chemistry: An interdisciplinary research across electrocatalysis and asymmetric synthesis

Abstract

The progress of chiral electroorganic chemistry, an emerging field in asymmetric organic synthesis and electrocatalysis, is summarized in this work. In recent years, with the intensive research of asymmetric organic synthesis and the rapid development of electrocatalytic organic synthesis, asymmetric electrochemical reactions have attracted the attention of researchers. The use of electrochemical methods is propitious to the controllability of product, and greenness, sustainability, repeatability of the process to synthesize enantiomers. From the organic chemical point of view, this review highlighted the reaction types with various electrochemical strategies, that is, the applications of electroreduction, electrooxidation, and electrochemical chiral resolution, respectively, for classified asymmetric electrosynthesis, and a longitudinal discussion is also conducted in each type of electroorganic reactions in different enantioselective strategies. This summary provides deep and systemic insights on the application of electrochemical methods in asymmetric organic synthesis.