Chiral electrochemical recognition of tryptophan enantiomers by polysaccharide modified MOFs

Abstract

Chiral discrimination plays an essential role in the fields of medicine, food science, life science, and materials science. So we synthesized CMC-MIL-88(Fe). A chiral material was synthesized by the amidation reaction between MIL-88(Fe)NH2 and sodium carboxymethyl cellulose (CMC). The post-modified chiral material CMC-MIL-88 (Fe) was successfully prepared as revealed by X-ray diffraction (XRD), Infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS), which was then modified on a glassy carbon electrode (GCE) to form an electrochemical chiral platform for the detection of tryptophan (Trp). The method then used to describe the electrochemical behaviour of the chiral platform is cyclic voltammetry (CV). The method used to explore the stereoselective identification of the Trp enantiomer is differential pulse voltammetry (DPV). The results showed that CMC-MIL-88(Fe)/GCE exhibited better selectivity towards l-Trp, with an enantioselectivity coefficient of 2.04. The effects of incubation time and pH on sex recognition were also investigated to optimise the parameters. This strategy has excellent sensitivity and high selectivity, which opens a new way for the recognition of Trp enantiomers.