Abstract

The chiral discrimination ability of two β‐cyclodextrin derivatives (hosts) having a flexible pyrrolidinylidenesulfamido‐appended moiety has been studied for the enantiomers of tolterodine tartrate (guest). Quenching of the fluorescence intensities of guests was observed in the presence of hosts. The S‐enantiomer of the tolterodine tartrate was better recognized by these hosts. Enantioselectivity factors (α) and association constants (Ks) of the host–guest complexes were calculated.

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