Abstract
Enantioselective C–H functionalization is a powerful tool for synthesizing chiral molecules. In the past few years, the combination of high-valent group 9 metals with achiral Cpx ligands and chiral carboxylic acids (CCA) has emerged as a promising catalytic system to enable selective cleavage and functionalization of enantiotopic C–H bonds. This Perspective summarizes the background, catalyst design, and applied reactions in detail, followed by a discussion of future directions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
