Abstract
Objective To investigate the prevention of multi-drug-resistant infections of Chinese medicine bath decolonization combined with monitoring sensitive index in neurosurgical intensive care (NICU) patients. Methods A total of 520 NICU patients from January 2014 to December 2015 in neurosurgery department of one Jiangsu hospital and one Shaanxi hospital were divided into control group (from January 2014 to December 2014, n=260) and observation group (from January 2015 to December 2015, n=260) . Infection control standard were applied in both groups and sensitive indexes were monitored. Patients in control group received warm water bath with routine care, while patients in observation group received Chinese medicine bath combined with monitoring sensitive indexes. Infection of Klebsiella pneumoniae (ESBLs-KPN) , pan drug resistant acinetobacter baumannii (MDR/PDR-AB) and methicillin-resistant staphylococcus aureus (MRSA) were recorded and analyzed. The incidence rate of catheter-associated urinary tract infection (CAUTI) , central line-associated bloodstream infection (CLABSI) and ventilator associate pneumonia (VAP) and prognosis of patients were compared between two groups. Results The rate of ESBLs-KPN infection, MDR/PDR-AB infection, MRSA infection, proportion of bacterial infection species≥2, proportion of colonies number≥10 cfu/cm2, proportion of antibiotics usage, incidence rates of CAUTI, CLABSI and VAP in observation group were significant lower than in control group (χ2= 7.688, 13.147, 11.183, 8.827, 9.931, 24.449, 39.389, 4.551, 11.269; P<0.05) . The time of in NICU and hospitalization in observation group were shorter than control group (t=-18.469, -36.914; P<0.05) . The score of satisfaction rate of patients in observation group was higher than control group (t=-39.946, P <0.05) . Conclusions Chinese medicine bath effectively reduces bacterial colonization in patients, prevents multi-drug resistant infection in NICU patients and decreases usage of antibiotics. Combination of Chinese medicine bath and monitoring sensitive indexes strength infection control, improve nursing quality so as to promote the prognosis and satisfaction of patients. Key words: Chinese medicine bath; Decolonization; Sensitive index; Neurosurgery; Intensive care; Multi-drug resistant infections
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