Abstract

The components of Zhibitai capsules are based on classic Chinese traditional medicinal formula, including natural statin, statin homologue, triterpenes and flavonoids. Zhibitai capsules is effective on dyslipidemia by inhibiting cholesterol synthesis and absorption. Several randomized clinical trials in Chinese patients have shown that Zhibitai capsules could reduce low density lipoprotein cholesterol (LDL-C) by 18%-34% and triglycerin (TG) by 30%.Zhibitai capsules had less side effects compared to statins, which interpreted a synergistic effect with Zhibitai capsules. Although no evidence has been proved to use Zhibitai capsules as prophylaxis of cardiovascular diseases, Zhibitai capsules is still an alternative choice of both primary and secondary prophylaxis of cardiovascular diseases.

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