Abstract

Allergen specific immunoglobulin E (sIgE) test plays a key role in pathogenic diagnosis of allergic diseases. In recent years, several in vitro diagnostic methods and technology are available in clinical application, however, there exists discrepancies due to different diagnostic methodology and lacking interlaboratory commutability. Proper interpretation of sIgE reports needs combination with clinical history and (or) other diagnostic methods. There is no accessible clinical interpretation approach in clinical practices. Thus, the consensus summarizes the aspects of in vitro diagnostic techniques, allergen items and clinical implications, expert panel draft the clinical interpretation approach which aims to provide a reference for community physicians, allergists, laboratory physician and other health care givers, and finally avoid misdiagnosis and mistreatment of allergic diseases.

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