Abstract
Immune-related keratopathy is a type of corneal disease caused by systemic or ocular immune disorders, with abnormal immune response to normal or degenerated corneal tissue, leading to the damage to ocular structure and function and the visual impairment. It mainly includes Mooren's ulcer, blepharokeratoconjunctivitis, and peripheral corneal ulcer associated with rheumatoid arthritis or other systemic immune diseases. Due to the diverse clinical manifestations, repeated and prolonged disease course, and high misdiagnosis and missed diagnosis rates, immune-related peripheral keratopathy often has a poor prognosis. The Cornea Group of Ophthalmology Branch of Chinese Medical Association has convened experts to discuss and reach the current consensus, focusing on the principle of diagnosis, differential diagnosis, and treatment of immune-related peripheral keratopathy, which would play an important clinical guiding role in the early detection, timely intervention, and proper treatment of the disease.
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