Abstract
Mast cell activation syndromes (MCAS) are divided into 3 groups based on mast cell (MC) clonality and activation triggers. Primary MCAS diseases are due to clonal expansion and MC proliferation that are typically associated with mutations in KIT as found in mastocytosis and monoclonal mast cell activation syndrome. Secondary MC disorders are in response to allergic or other inflammatory diseases causing MC activation. Idiopathic MCAS is diagnosed when no clonal MC disease and other etiologic mechanisms have been identified.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
