Childhood trauma: a risk for major depression in patients with psoriasis

Mercede Erfanian

doi:10.1080/24750573.2018.1452521

Abstract

ABSTRACTINTRODUCTION: A history of childhood trauma is an important determinant for understanding the development of psychiatric and physical disorders. The chronic inflammatory disease, psoriasis, has been reported to be affected by childhood psychological stressors. Early life stress is also a well-known contributor to major depression. The current study aims to clarify a possible association between levels and types of childhood trauma with psoriasis severity and major depression.METHOD: Sixty-four patients diagnosed with mild-to-severe psoriasis (male = 27, mean age = 52.51 ± 14.72 years and female = 37, mean age = 42.76 ± 14.45 years, age range = 21–77) were admitted to our study between April 2014 and September 2014. For the diagnosis of psoriasis, the single most recently developed lesion was examined dermoscopically and histopathologically. We evaluated the history of childhood trauma with the Childhood Trauma Questionnaire and diagnosis of major depression with the Mini International Neuropsychia...

Highlights

A history of childhood trauma is an important determinant for understanding the development of psychiatric and physical disorders
The current study aims to clarify a possible association between levels and types of childhood trauma with psoriasis severity and major depression
We evaluated the history of childhood trauma with the Childhood Trauma Questionnaire and diagnosis of major depression with the Mini International Neuropsychiatric Interview (MINI 5.0.0 current)

Summary

Introduction

A history of childhood trauma is an important determinant for understanding the development of psychiatric and physical disorders. The current study aims to clarify a possible association between levels and types of childhood trauma with psoriasis severity and major depression. RESULTS: Emotional (0.325), physical (0.614), sexual (0.963) abuse, and emotional (0.331) neglect were positively correlated with higher severity of psoriasis (p < .01). Emotional (U = 372, p = .43), physical (U = 387, p = .049), sexual (U = 297, p = .0005) abuse, emotional (U = 299.5, p = .001), and physical U = 372, p = .031) neglect were significantly higher in psoriasis patients with depression compared to non-depressed (p < .05). The increased level of emotional, physical, sexual abuse, and emotional neglect was linked to elevated severity of psoriasis. All childhood trauma subtypes appeared to be more severe in the group of psoriasis patients with major depression. Child physical neglect is the insufficient/ poor satisfaction of child’s physical and intellectual

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Conclusion