Abstract
Oral manifestations may be the first clinical signs of idiopathic thrombocytopenic purpura (ITP) diagnosed by a pediatric dentist. The aim of the present study was to describe oral manifestations and dental care for patients with ITP. A narrative review of the literature was performed, involving a search in the MEDLINE (PubMED) electronic database for relevant articles published in English using the following keywords:
Highlights
Thrombocytopenia is a blood disorder characterized by an accentuated reduction in platelets
A narrative review of the literature was performed, involving a search in the MEDLINE (PubMED) electronic database for relevant articles published in English using the following keywords: “Purpura, Thrombocytopenic, Idiopathic”, “Hematologic diseases” and “Dental care”
The inclusion criteria were studies that addressed oral manifestations and dental management in patients with idiopathic thrombocytopenic purpura (ITP). This condition is considered one of the most common blood disorders in children. Manifestations such as spontaneous or trauma-induced gingival bleeding, petechiae, hematomas, purpura and ecchymosis are reported in regions of the vestibular mucosa, lateral edges of the tongue and the junction between the hard and soft palate as well as other sites of the oral mucosa
Summary
Thrombocytopenia is a blood disorder characterized by an accentuated reduction in platelets. This reduction in number and function may stem from different mechanisms, such as autoimmune destruction, spleen sequestration, bone marrow failure, infiltration by tumor cells and an adverse drug reaction [1]. Idiopathic thrombocytopenic purpura (ITP) is one of the most common causes of symptomatic thrombocytopenia in children, [2,3] with the annual incidence of ITP is estimated to be between 1 and 6.4 cases per 100,000 children [2,4]. The most common clinical symptoms are hematoma, petichiae, bleeding of the mucous membranes and other hemorrhagic manifestations of thrombycytopenia [5,6,7]. The aim of the present study was to describe oral manifestations and care (pediatric dentistry) for patients with idiopathic thrombocytopenic purpura
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