Abstract
Pediatric epileptic encephalopathies comprises a group of severe childhood epilepsy syndromes characterized by refractory seizures associated with progressive cerebral dysfunction, manifesting as cognitive or learning difficulties and behavioural or sensory impairments.
Highlights
Encephalopathy is a descriptive term referring to diffuse brain disorder leading to altered brain function and/or structure
Pediatric epileptic encephalopathies are prevalent in our society, with epileptic spasms/West syndrome and Lennox-Gastaut syndromes leading the list
Perinatal asphyxia was the main risk factor identified among the cases
Summary
Encephalopathy is a descriptive term referring to diffuse brain disorder leading to altered brain function and/or structure. The term epileptic encephalopathy (EE) was introduced by the International League Against Epilepsy (ILAE) 2001 diagnostic scheme, as a condition in which epileptiform abnormalities are believed to contribute to the severe cognitive and behavioural impairments beyond what is expected from the underlying pathology [1,2]. There is dearth of information on childhood EE among African children with epilepsy. To the best of our knowledge, this is the first specific report on the profile of childhood EE among Nigerian children as well as West African sub-region. Pediatric epileptic encephalopathies comprises a group of severe childhood epilepsy syndromes characterized by refractory seizures associated with progressive cerebral dysfunction, manifesting as cognitive or learning difficulties and behavioural or sensory impairments
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
