Chilblain-Like Lesions during COVID-19 Pandemic: The State of the Art.

Andrea Bassi,Carlo Mazzatenta,Elisabetta Venturini,Giuseppe Argenziano,Teresa Russo,Vincenzo Piccolo,Iria Neri

doi:10.3390/life11010023

Abstract

SARS-CoV-2 infection has spread all over the world in the last year, causing millions of COVID-19 cases among humans with a large variability of symptoms and signs, including those on the skin. Among these, a contemporary cluster of chilblain-like lesions with no certain relationship with the infection has been reported. The aim of this paper is to delineate a profile of chilblain-like lesions and to establish the state-of-the-art knowledge about this new phenomenon.

Highlights

Published: 2 January 2021SARS-CoV-2 infection has spread all over the world in the last year, causing millions of COVID-19 cases among humans with a large variability of symptoms and signs, resulting in mild to very severe and sometimes lethal outcomes
Respiratory symptoms are the most common, other findings could affect patients with COVID-19, including quite nonspecific cutaneous signs, such as urticarial, macular papular rash, and varicella-like eruptions. While the latter have been observed in patients with proven infection [1,2], during the first phases of the COVID-19 pandemic, a contemporary cluster of chilblain-like lesions with no certain relationship with the infection has been reported [3]
The aim of this paper is to delineate a profile of chilblain-like lesions and to establish the state-of-the-art knowledge about this new phenomenon

Summary

Introduction

SARS-CoV-2 infection has spread all over the world in the last year, causing millions of COVID-19 cases among humans with a large variability of symptoms and signs, resulting in mild to very severe and sometimes lethal outcomes. Respiratory symptoms are the most common, other findings could affect patients with COVID-19, including quite nonspecific cutaneous signs, such as urticarial, macular papular rash, and varicella-like eruptions. While the latter have been observed in patients with proven infection [1,2], during the first phases of the COVID-19 pandemic, a contemporary cluster of chilblain-like lesions with no certain relationship with the infection has been reported [3]. The aim of this paper is to delineate a profile of chilblain-like lesions and to establish the state-of-the-art knowledge about this new phenomenon

Chilblain-Like Lesions

The State of the Art and Future Perspectives