Abstract
In 2019, an outbreak of chikungunya virus infection occurred in Mandalay, Myanmar, and 3.2% of blood donors and 20.5% of patients who were children were confirmed as being infected. The prevalence rate was up to 6.3% among blood donors. The East Central/South African genotype was predominantly circulating during this outbreak.
Highlights
Khin Mar Myint, Ei Phyu Lwin, Hlaing Myat Thu, Corazon C Buerano, Kyaw Zin Thant, Kouichi Morita
Amino acid sequences of the partial E 1 protein of the infecting 2019 CHIK virus (CHIKV) strains in this study showed no envelope protein 1 (E1):A226V mutation (Table, https://wwwnc.cdc. gov/EID/article/26/11/20-1824-T2.htm)
We showed that 3.2% of blood donors and 20.5% of children had CHIKV infections during the CHIK outbreak in Myanmar in 2019
Summary
The proportion of confirmed CHIKV cases among blood donors had an increasing trend from June through September: prevalence rates were 1.1% in June, 0.9% in July, 2.5% in August, and 6.3% in September (p = 0.02) (Figure 1). 19 had an acute viral infection and 4 had neurologic manifestations, and all blood donors were asymptomatic (Table 1). Amino acid sequences of the partial E 1 protein of the infecting 2019 CHIKV strains in this study showed no E1:A226V mutation Phylogenetic trees for partial E1 and NS1 genes [11] showed that our virus strains belonged to the Indian Ocean clade of the ECSA genotype and were similar to those circulating in India and Thailand and previously circulating in Myanmar (Figure 2)
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