Abstract
Chest X-Ray Findings in Drug Sensitive and Drug Resistant Pulmonary Tuberculosis Patients in Uganda
Highlights
IntroductionRadiology has an important role in the diagnosis of both drug-sensitive (DS) and drug-resistant (DR) pulmonary TB (PTB)
Tuberculosis (TB) is one of the leading causes of death worldwide
We observed that a vast majority of participants had similar chest x-ray (CXR) changes, irrespective of drug susceptibility status
Summary
Radiology has an important role in the diagnosis of both drug-sensitive (DS) and drug-resistant (DR) pulmonary TB (PTB). This study aimed at comparing the chest x-ray (CXR) patterns of microbiologically confirmed cases of DS and DR PTB in Uganda. Tuberculosis (TB) is one of the leading causes of mortality globally [1]. An estimated 206,030 cases of drug-resistant (DR) TB were reported, reflecting a 10% increase from the year 2018 [1]. Chest X-ray (CXR) is the primary radiologic evaluation of suspected or proven pulmonary TB (PTB) [2]. Several factors have been shown to affect CXR findings in patients with PTB; namely, human immunodeficiency virus (HIV) infection and the degree of immunosuppression, previous treatment for PTB and microbiological profile, that is drug-sensitive (DS) or DR-TB [4]. Some studies suggest that DS and DR-TB present differently on the CXR in terms of morphology, size and location of the lesions, a detailed description of the difference in CXR findings between DS- and DR-TB is not widely published[4, 5]
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