Abstract
In cancer patient during or following oncologic therapies with respiratory symptoms and pulmonary pathology at chest CT the differential diagnosis includes infection, therapy-induced disease and tumour progression.Although CT morphology may be typical or even pathognomonic in some conditions the diagnosis is usually made by a synopsis of imaging, clinical and laboratory features.Close communication with referring colleagues and a good knowledge of potential side effects of therapeutic concepts, their time course and CT morphology is crucial in the differential diagnosis.This review describes a personal approach to the radiological diagnosis of therapy-induced pulmonary abnormalities in cancer patients.
Highlights
Why imaging for pulmonary complications of oncologic therapy? In patients during or following therapy for cancer pulmonary symptoms are common
This review describes a personal approach to the radiological diagnosis of therapy-induced pulmonary abnormalities in cancer patients
In patients with suspected pneumocystis jirovecii pneumonia (PCP) chest CT may be helpful to demonstrate the typical pattern of CT technique Intravenous contrast medium If the detection and/or classification of pulmonary pathology is the sole indication for imaging unenhanced CT is usually sufficient
Summary
Why imaging for pulmonary complications of oncologic therapy? In patients during or following therapy for cancer pulmonary symptoms are common. Other disease with increased risk in cancer patients Cryptogenic organizing pneumonia (COP) manifests as solitary or multiple peripheral areas of consolidation, pulmonary nodules or masses, peribronchovascular consolidation or other morphology. In patients with suspected PCP chest CT may be helpful to demonstrate the typical pattern of CT technique Intravenous contrast medium If the detection and/or classification of pulmonary pathology is the sole indication for imaging unenhanced CT is usually sufficient.
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