Abstract
Cherubism is described as a rare and benign hereditary bone disease, characterized by a bilateral volumetric increase in the maxillary bones, with a greater predilection for males in childhood. Clinically, it presents as a volumetric enlargement of the mandible and, maxilla, which is generally painless, firm on palpation and varies in relation to size and extension. Its differential diagnosis is the Brown Tumor of Hyperparathyroidism and the Central Lesion of Giant Cells. The diagnosis is based on the assessment of clinical characteristics together with complementary exams. The objective of this study was to carry out a brief review of the literature and report a clinical case of this pathology in a 9-year-old child with a family history of cherubism, assessed through imaging, histopathological and karyotype exams, which continues to be assisted by the oral and maxilofacial surgery team of the Faculdade de Odontologia de Araçatuba - FOA Unesp since the treatment of the cherubism still does not have a definitive protocol.
Highlights
The term Cherubism was first reported in the literature by Dr W
This study is a case report in a qualitative and descriptive way, associated with a narrative review of the literature, bringing relevant data available in the literature, regarding the pathology correlated to the clinical case presented of a 9-yearold male patient, with suspected cherubism and a positive diagnosis of cherubism in family history that was accompanied by the maxillofacial surgery and traumatology team at the Faculty of Dentistry of Araçatuba - UNESP
The importance of detailed evaluation of image exams, especially of computed tomography, which allows the accurate visualization of the involvement of all facial structures, is noteworthy, in addition to the importance of monitoring the case to assess the progression of the disease, since the cherubism does differential diagnosis with many other diseases and its treatment still does not have a defined protocol
Summary
The term Cherubism was first reported in the literature by Dr W. Some researchers (Oliveira et al, 2008; Yalcin et al, 1999) believe that its etiology is associated with the gene linked to the development of the maxillary and mandibular bones and agree that lesions regress spontaneously at puberty (Tiziani et al, 1999; Dias & Guedes, 1999; Chrcanovic et al, 2020; Cardoso et al, 2012, Beaman et al, 2004; Cariati et al, 2017). The reason for this has not yet been established and the most likely hypothesis is that sex hormones act on bone cells and normalize the situation (Oliveira et al, 2008)
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
