Abstract

Content organisation Cardio toxic effect of chemotherapy is a well-recognised problem in cancer patients. Cardio toxicity depends on multiple predisposing factors, specific components of the chemotherapy regimen, length of treatment, and dosage. We will present the spectrum of most common cardiotoxic chemotherapy agents and their combinations, specific effects on the myocardium, and imaging features of cardiomyopathies induced by chemotherapy. We will review pathophysiology of chemotherapy induced cardiomyopathy including:

Highlights

  • Learning objectives To review the spectrum of imaging findings of chemotherapy- induced cardiomyopathy in correlation with most common cytotoxic drugs and regimens

  • We will present the spectrum of most common cardiotoxic chemotherapy agents and their combinations, specific effects on the myocardium, and imaging features of cardiomyopathies induced by chemotherapy

  • Chemotherapy induced cardiomyopathy is a common problem among cancer patients, increasing long term morbidity and mortality and often leading to disability

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Summary

Open Access

Chemotherapy induced cardiomyopathy: an overview, imaging features, and future prospective. From International Cancer Imaging Society Meeting and 15th Annual Teaching Course (ICIS 2015) London, UK. Learning objectives To review the spectrum of imaging findings of chemotherapy- induced cardiomyopathy in correlation with most common cytotoxic drugs and regimens. Content organisation Cardio toxic effect of chemotherapy is a well-recognised problem in cancer patients. Cardio toxicity depends on multiple predisposing factors, specific components of the chemotherapy regimen, length of treatment, and dosage. We will present the spectrum of most common cardiotoxic chemotherapy agents and their combinations, specific effects on the myocardium, and imaging features of cardiomyopathies induced by chemotherapy. We will review pathophysiology of chemotherapy induced cardiomyopathy including:. Dose dependent cardiomyopathy Predisposing conditions –diabetes, presence of coronary artery disease, age. Dose dependent cardiomyopathy Predisposing conditions –diabetes, presence of coronary artery disease, age. Potential reversibility

Conclusions
We will discuss imaging characteristics of chemotherapy induced cardiomyopathy
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