Abstract
Publisher Summary The reflex rise of arterial pressure is an extremely sensitive indicator of tissue receptor excitation that is caused by endogenic substances. There are two kinds of pressor reflexes. The first kind arises in response to stimulation by substances with concentrations several orders lower than the algogenic ones. These reflexes are termed as “specific.” The second kinds are evoked by substances in algogenic concentrations. They are large, and what is especially important, have a high rate of arterial pressure rise. This kind of reflex is nociceptive—that is, represents the circulatory component of the defence reaction. The effective concentrations for both, the second kind of reflex and for chemalgia, are the same. The non-algesic substances—for example, tryptophan, methacholine, and pilocarpine—evoke only specific reflexes on exciting sensory nerve endings in the organ. Potentially algogenic substances, when used in concentrations many orders lower than the algesic ones, have the same effect.
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