Chemoselectivity of 2‐Arylmethyleneaminoisoindolin‐1,3‐diones toward Arenes under Friedel–Crafts Conditions: An Efficient Synthesis of Benzophenones Integrated with 2‐Substituted Hydrazone Moieties

Abstract

Treatment 2‐arylmethyleneaminoisoindole‐1,3‐diones 1a–c with arenes in the presence of AlCl3‐DMF complex as a catalyst afforded the novel compounds, 2‐((arylidenehydrazono)(aryl)‐methyl)benzophenones 3a–n in satisfactory yields. The structure of the obtained products 3a–n was confirmed by the use of IR, 1H‐NMR, 13C‐NMR, mass spectra, and elemental analyses.