Abstract
A green and efficient procedure is reported for the chemoselective reduction of nitroarenes catalyzed by a highly active alumina-supported cobalt nanocatalyst in the presence of hydrazine hydrate. The nanocatalyst can be applied under mild reflux conditions for the synthesis of arlyamines in high yields. Moreover, the catalyst can be easily recovered by simple filtration and reused several times without obvious loss in its catalytic activity.
Highlights
Arylamines are industrially important organic intermediates and attractive compounds for the chemical synthesis due to their wide utility in fine chemicals dyes and polymers.[1]
In continuation of our studies on the catalytic activity of different nanocatalysts on organic reactions,[31,32,33,34,35,36] we report an efficient and green procedure for the chemoselective reduction of nitroarene compounds catalyzed by cobalt nanoparticles supported on Al2O3 support (Co/ Al2O3 nanocatalyst) in ethanol under reflux conditions (Scheme 1)
Results confirmed that cobalt nanoparticles supported on Al2O3 support (Co/Al2O3 nanocatalyst) can be considered as an simple, efficient, green and recyclable nanocatalyst for the synthesis of various functionalized arylamines
Summary
Arylamines are industrially important organic intermediates and attractive compounds for the chemical synthesis due to their wide utility in fine chemicals dyes and polymers.[1]. A variety of metallic catalysts and methods were reported for the synthesis of arylamines.[4,5,6,7,8,9,10,11,12,13,14,15,16] some of these catalysts possess the lack of chemoselectivity, adaptability to nitro-containing substrates and recyclability. Some of these methods incude the use of toxic solvents, hard work-up, low selectivity and harsh reaction conditions. The catalytic activity need to be further improved, and introduction of alternative methods for the chemoselective reduction of nitroarenes to their corresponding arylamines in terms of potential simplicity, high activity and environmental process is still in demand
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
