Abstract

Clinical progression of Prostate Cancer (CaP) is variable: some tumours are indolent, others
 rapidly progress. Because, diagnosis is usually in elderly men, CaP is an ideal target for
 chemoprevention. We showed that Green Tea Catechins (GTC) possess anti-tumour activity,
 suggesting that it might be beneficial in the early stages of cell transformation. But an experimental
 confirmation in a real clinical setting was needed. High-Grade Prostatic Intraepithelial Neoplasia
 (HGPIN) is a pre-invasive stage of CaP for which no treatment options are available until CaP is
 diagnosed.

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