Abstract
OPINION article Front. Immunol., 26 May 2015Sec. Cytokines and Soluble Mediators in Immunity Volume 6 - 2015 | https://doi.org/10.3389/fimmu.2015.00246
Highlights
Specialty section: This article was submitted to Chemoattractants, a section of the journal Frontiers in Immunology
It was not known at the time, the chemokine field started with the identification of a protein by Heparin Sepharose affinity chromatography, platelet factor 4 (PF4) [1] called CXCL4 in the systemic nomenclature introduced in 2000
This interest was inspired by the paper recently published by Antal Rot demonstrating the evidence for haptotaxis as opposed to chemotaxis [2], earning him the title of Godfather of Chemokine–GAG biology
Summary
Specialty section: This article was submitted to Chemoattractants, a section of the journal Frontiers in Immunology. NovImmune, Geneva, Switzerland Keywords: chemokines, glycosamininoglycans, RANTES, GAG mutants, oligomerization
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