Abstract
Abstract Objective To estimate an accurate level of IL-8 in aqueous humor among open-angle glaucoma (OAG) patients. Methods Meta-analysis was performed from available studies that investigated the IL-8 level in the aqueous humor of OAG patients and control subjects. Results A total of 17 studies were selected. The pooled result showed that IL-8 levels in aqueous humor of patients with OAG were higher than in control subjects (SMD = 0.98, 95 % CI = 0.68–1.27, p Conclusion This meta-analysis indicates that patients with OAG may have higher aqueous humor IL-8 levels compared to control subjects, which supports the notion that IL-8 is one of the contributing factors in the development of OAG.
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