Abstract
Sulphur heterocyclic β-hydroxy nitriles are prepared from the suitable aldehyde and (trimethylsilyl)acetonitrile in the presence of lithium acetate at good yields. Burkholderia cepacia lipase allowed the formation of the both enantiomers of β-hydroxy nitriles in highly enantiopure forms (ee 99%) through acylation of a racemic mixture and alcoholysis of the acylated enantiomer in tert-butyl methyl ether.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
