Abstract

In the structure of the incidence of malignant tumors for a number of years, colorectal cancer occupies one of the leading positions, with a steady tendency to growth. The five-year survival rate of patients with metastatic liver damage in colorectal cancer does not exceed 28%. A significant breakthrough in the study of the biology of colorectal cancer has led to a deep understanding of individual processes of carcinogenesis and a personalized approach to treatment tactics. Despite this, the problem of chemoresistance remains one of the most acute. The high toxicity of systemic chemotherapy limits its use in this group of patients. In this connection, minimally invasive and at the same time effective methods of local treatment of malignant liver tumors have been introduced into clinical practice. These methods include: hepatic artery chemoinfusion, chemoembolization, oil chemoembolization and radioembolization. At present, a large world experience has already been accumulated in the application of the above-described methods of treatment. However, the question of the application of methods of interventional surgery in the treatment of patients with chemoresistant metastases is still open. The presented review reflects the results of the analysis of scientific literature on the treatment of this group of patients. The main stages of development and improvement of X-ray endovascular methods of treatment are presented.

Highlights

  • Введение Колоректальный рак (КРР) на сегодняшний день остается актуальной проблемой современной онкологии [1, 2, 3]

  • A significant breakthrough in the study of the biology of colorectal cancer has led to a deep understanding of individual processes

  • most acute. The high toxicity of systemic chemotherapy limits its use in this group of patients

Read more

Summary

Introduction

Введение Колоректальный рак (КРР) на сегодняшний день остается актуальной проблемой современной онкологии [1, 2, 3]. При отсутствии специального противоопухолевого лечения метастатического поражения печени, медиана продолжительности жизни не превышает 11 месяцев [2, 17]. Были опубликованы результаты 250 эмболизаций печеночной артерии у пациентов с метастазами в печень [24]. Основные внутрисосудистые методы лечения колоректальных метастазов в печени включают в себя: эмболизацию воротной вены; химиоинфузию (ХИПА), эмболизацию и химиоэмболизацию печеночной артерии, радиоэмболизацию.

Results
Conclusion
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call