Abstract

The aim of current work was to determine essential oils (EOs) composition from three Eucalyptus species, including E. citriodora, E. camaldulensis and E. globulus and assess their α-glucosidase inhibitory activity. The EOs were collected using the hydrodistillation technique and characterized by GC/MS, GC-FID and NMR. The isolated EOs from leaves parts of Eucalyptus species varied from 0.56 to 1.0% on fresh weight basis. The content of the EOs was distinct according to the species. The most abundant metabolites were identified as citronellal (0-83.0%), 1,8-cineole (0.2-44.8%), spathulenol (0.4-16.1%) α-pinene (0.4-15.9%), p-cymene (3.7-11.9%), citronellol (0-8.6%), β-eudesmol (5.3-8.6%) and β-pinene (0-7.1%). The EOs obtained from targeted samples exhibited strong α-glucosidase inhibitory activity. These results are encouraging and underline that the EOs of Eucalyptus species may be a promising alternative source of natural antidiabetic.

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