Abstract

An acyl group attached to the 2-position of the thiazole ring is removed hydrolytically by hot mineral acid generating the related carboxylic acid which is identified as its p-nitrobenzyl ester by t.l.c. Direct chemical evidence has thus been obtained for the presence of a propionyl group in dimethyl micrococcinate. The procedure is applicable down to about the 0·5 µmole scale.

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