Chemistry of medicinal plants as an integral part of ecological education

Tetiana Derkach,Hanna Tarasenko,S Semerikov,S Sakhno,S Chukharev,H Danylchuk,A Striuk,O Bondarenko,T Vakaliuk,P Nechypurenko,V Osadchyi,A Iatsyshyn,S Klimov

doi:10.1051/e3sconf/202128011015

Abstract

The degree of variability in the composition of herbal medicines was studied on the example of the preparation of St. John's wort from various Ukrainian producers. The Cu and Zn contents were the most stable compared to other (Fe, Mn, Co, Cr, Ni, Pb, Cd) microelements among plants of different origins. The content of toxic elements (Pb, Cd) did not exceed the established standards. Meanwhile, a 2-3-fold concentration difference was observed for hyperforin, an active pharmaceutical ingredient in St. John’s wort. Thus, the existing standards do not ensure the stability of the composition of herbal preparations. As a result, the quality of medicinal drugs can be significantly different. The key reason for the variation in plant composition is environmental influence, including anthropogenic factors. Existing training programs for prospective specialists of the pharmaceutical industry do not pay enough attention to the impact of the environment on the quality of herbal raw materials. Necessary changes to the syllabi of relevant disciplines are formulated to eliminate this shortcoming and ensure sustainable development of raw materials sources for the pharmaceutical industry.

Highlights

Medicinal plants have a long millennial history of use
Most herbal medicines belong to the group of overthe-counter medication and are consumed by patients in self-medication
Medicinal plants and herbal medicines are widely represented in the market of Ukraine

Summary

Introduction

Medicinal plants have a long millennial history of use. Even today, they remain an essential part of modern medicine [1]. About 25% of medications used worldwide are obtained directly from medicinal plants. They are used by pharmaceutical companies and in food, confectionery, cosmetics, paints, and varnishes. Most herbal medicines belong to the group of overthe-counter medication and are consumed by patients in self-medication. Some medicinal plants are toxic, primarily due to low quality and non-compliance with standards [4]. Some herbal medicines may have serious side effects or be ineffective [5]. Herbal remedies are not usually adequate to treat any acute illness [6]

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Conclusion