Abstract
A convenient three-step one-pot copper-catalysed method has been developed for the preparation of pyrazolo[4,3-b]indoles, new indole-based compounds with potential biological activity. Treatment of various hydrazines, including alkyl hydrazines, with indole-2-carbaldehydes generated the corresponding products in moderate to good yields without protection of the indole N-1 moiety. In addition, LiOH was used as a base in the copper-catalysed coupling reaction. Microwave heating was used to accelerate the iodination of indoles and the C–N bond formation.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
