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Abstract
Abstract Tartaric acid, regioselective saponification, Pig Liver Esterase, 3-methoxy-2-azetidinone, N -Hydroxy-2-thiopyridone, radical decarboxylation. The synthesis of 3α-alkoxy-4β-azetidinones from L(+) tartaric acid is described. Regioselective saponification and methylation along with a stereo selective radical decarboxylative alkylation are key steps leading to optically pure trans-β-lactams.
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