Abstract

A series of new substituted-[1,2,4]oxadiazolo[5,4-d][1,5]benzothiazepine derivatives containing pyrazole ring 4/4′ was synthesized by substituted-pyrazolo[1,5]benzothiazepines 2/2′ and substituted-benzohydroximinoyl chlorides 3 through the 1,3-dipolar cycloaddition reaction in the presence of Et3N at room temperature, and characterized by MS, IR, 1H NMR and elemental analyses. In addition, the structure of 4′l was determined by X-ray crystallography. J. Heterocyclic Chem., 2011.

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