Abstract
Abstract The mesylates used as protecting groups to permit the formation of bis(polypropionates) via the non-aldol aldol process can be easily displaced with good nucleophiles, e.g., azide, thioacetate, acetate, to generate β-azido (and β-amino) alcohols, β-thioacyl alcohols, and aldols of the opposite chirality, e.g., syn isomers afford anti products. Thus the anti mesylate 15 affords the all-anti mzido aldol system 16 in good yield.
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