Abstract

Abstract The selective deuterations of several chalcones and related flavonoids were carried out with a catalytic amount of KOH in methanol-d 1 . Product formation showed exclusively α-deuteration with the exception of 2-styryl-chromone, which was completely deuterated at the γ position. Product formations were verified by 1 H and 13 C NMR spectroscopy and several reactions were monitored by 1 H NMR spectroscopy.

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