Abstract
Nanodomain Pd(0) mediated regio- and stereo-selective synthesis of (Z)-3-methyleneisoindoline-1-ones and furo[3,2-h]quinolines in water was achieved in high yield. The novel one-pot domino-Sonogashira-cyclization protocol is environment friendly as it eliminates the use of ligands, copper, organic solvents or ionic liquids and homogeneous catalysts. More importantly, the nanocatalyst can be recovered in high yield and recycled for five consecutive reactions without any significant loss of reactivity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have