Abstract
Abstract The sulfonium ylide derived from (1R, 2S, 3R, 5S)-2,3-dibenzyl-1,8,8-trimethyl-3-thianiumbicyclo[3.2.1]octane perchlorate 6 (prepared from (1R,3S)-(+)-camphoric acid) transfers its benzylidene group to some carbonyl compounds with ee's approaching enandomeric purity. It is suggested that in this system the chiral induction is due to the facial selectivity at the ylide rather than the carbonyl carbon.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have