ChemInform Abstract: Palladium‐Catalyzed Z‐Selective Oxidative Amination of ortho‐Substituted Primary Anilines with Olefins under an Open Air Atmosphere.

Abstract

The Pd-catalyzed oxidative amination of olefins with primary anilines has been achieved using molecular dioxygen as the sole oxidant. The use of ortho-substituted primary anilines such as ortho-toluidine was the key to the successful development of this reaction, providing the corresponding N-alkenyl substituted anilines in high yields with unusually high levels of Z-selectivity.