Abstract
A discussion on the molecular design of solid catalysts is presented. Rather than reviewing the many definitions of design principles and methodologies for synthesis of classes of catalysts, a specific case study is provided. Salient features of protein-based (enzyme, antibody) catalysts are enumerated and used to guide the creation of two new types of solid catalytic materials, namely, organic functionalized molecular sieves and amorphous imprinted organosilicates. The solid catalysts are compared to an antibody catalyst and their behaviors contrasted.
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