ChemInform Abstract: Microwave‐Assisted Copper‐Powder‐Catalyzed Synthesis of Pyrimidinones from β‐Bromo α,β‐Unsaturated Carboxylic Acids and Amidines.

Abstract

β-Bromo α,β-unsaturated carboxylic acids were coupled and cyclized with amidine hydrochlorides by microwave irradiation in the presence of catalytic amounts of copper powder and a base to give the corresponding pyrimidinones in high yields.