Abstract

AbstractTo understand the relationships of both mechanisms and the acidity of the reaction, the SN1 and SN2 deprotection mechanisms for synthetic peptides with O‐benzyl protecting groups were studied in a ternary mixture of trifluoromethanesulfonic acid (TFMSA) ‐ trifluoroacetic acid (TFA) ‐ dimethyl sulfide (DMS).

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