ChemInform Abstract: Lipase-Catalyzed Kinetic Resolution with in situ Racemization: One-Pot Synthesis of Optically Active Cyanohydrin Acetates from Aldehydes.

Abstract

at will. Although the capacity shown here compares more than well with, for example, a biological alternative method using the protein cellulasea [the amounts of timolol with optimal base-line separation were 18.9 and 19.9 pg/g of dry CSP, respectively (Figure 2), and in connection with the aforementioned polarimetric study of propranolol, with fair resolution but no base-line separation, 400 p g / g of dry CSP], work aimed at increasing the capacity of analogous imprinted polymers is in progress and will further increase the applicability of the technique for (semi)preparative isolation of pure enantiomers of compounds such as &blockers. However, we feel that already today the removal of contaminating small amounts of the nondesired enantiomer may be feasible on a technical scale with the described technique.