ChemInform Abstract: Highly Regio‐ and Diastereoselective Addition of Organolithium Reagents to Chiral Fluoroalkyl α,β‐Unsaturated N‐tert‐Butanesulfinyl Ketimines: A General and Efficient Access to α‐Tertiary Fluoroalkyl Allylic Amines and α‐Fluoroalkyl α‐AminoAcids.

Abstract

AbstractThe target α‐fluoroalkyl amino acids are accessible via a 6‐step sequence in high overall yield with retention of the newly generated stereocenter.