ChemInform Abstract: Expedient Introduction of β‐Methoxyacrylate Unit onto 3‐Substituted Indoles and Application of the Resulting Indole‐Dienes in Organocascade Toward Indolino‐Polycyclics.

Abstract

AbstractAn efficient methodology for introducing a β‐alkoxy acrylate unit onto the C‐2 position of 3‐substituted indoles is realized by oxidative radical alkylation of indoles with a xanthate bearing a dialkyl acetal functionality and subsequent elimination of alcohol by treatment with DBU.