Abstract
AbstractThe 50‐mmol‐scale synthesis of N‐acetylneuraminic acid (Neu5Ac) (Ia) from pyruvate and N‐acetyl‐D‐mannosamine (ManNAc) catalyzed by Neu5Ac aldolase and a small‐scale (0.32 mmol) synthesis of Neu5,9Ac2 (Ib) from ManNAc by two separate enzyme reactions, catalyzed by protease N and Neu5Ac aldolase, resp., are described.
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