Abstract
Abstract A family of new chiral phosphoramidite ligands based on 3,3′-disubstituted ( S )-BINOL have been successfully synthesized. The chiral phosphoramidite ligands were subsequently applied to the copper(II)-catalyzed enantioselective addition of diethylzinc to β-substituted enones, giving the desired chiral adducts with enantioselectivities of up to 93% ee and high yields (up to 88%).
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