Abstract
Two novel chiral stationary phases derived from (R)- and (S)-1-(1-naphthyl) ethylamine with (R)-phenylglycine chemically bonded to (3-aminopropyl)silanized silica, [5] and [6], which contain two asymmetric carbon atoms attached to two nitrogen atoms of the ureylene group, have been prepared. These phases showed good enantioselectivity for derivatives of amino acid, amine, carboxylic acid and alcohol enantiomers. Especially excellent separation factors were obtained in enantiomeric separation of aromatic amine and carboxylic acid in the form of 3, 5-dinitrobenzoyl and 3, 5-dinitroanilide derivatives respectively upon phase [6]. It is noticed some enantiomers were resolved directly without any prederivatization on these phases. For example, enantiomers of both E- and Z-isomers of S-3308 (1-(2, 4- di chloropheny1)-4, 4-dimethy1-2-(l, 2, 4-triazol-1-y1)-1-penten-3-ol) are well resolved simul taneously with [5].
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
