Abstract
Abstract 1-Carbobenzoxy-3-carbomethoxy-5,6-dihydro-4-pyridone ((1) has proven to be exceptionally receptive in the conjugate addition of organocuprates to give C-2 substituted piperidones having the C-3 position activated toward alkylation. Enone (1) was used as the key synthon in the synthesis of C-1, C-2 and C-3 substituted 4-piperidinol (8).
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