Year-end Sale % OFF 
Abstract
A wide array of aldehydes undergo smooth cross-coupling with 3-hydroxy-3-(4-hydroxybut-1-en-2-yl)-1-methylindolin-2-one in the presence of 10 mol% BF3·OEt2 at 0 °C in dichloromethane to afford the corresponding 2,3,5,6-tetrahydro-1′H-spiro[pyran-4,4′-quinoline]-2′,3′-dione derivatives in good yields with excellent diastereoselectivity. This is the first report on the synthesis of tetrahydro-1′H-spiro[pyran-4,4′-quinoline]-2′,3′-dione scaffolds through a cascade of Prins/pinacol reactions.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
